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Selected Publications


Powell, M.D., Ghosh, M., Jacques, P.S., Howard, K.J., LeGrice, S.F., and Levin, J.G. (1997) Alanine-scanning Mutations in the "primer grip" of p66 mv-1 Reverse Transcriptase Results in Selective Loss of RNA Priming Activity. J. BioI. Chem. 272: 13262-13269.


Ghosh, M., Williams, J., Powell, M.D., Levin, J.G., Le Grice, S.F. (1997) Mutating a Conserved Motif of the mv-1 Reverse Transcriptase Palm Subdomain Alters Primer Utilization. Biochemistry 36:5758-5768.


Powell, M.D., & J .G. Levin. (1996) Sequence and Structural Determinants Required for Priming of Plus-Strand DNA Synthesis by the mv-1Polypurine Tract. J. Virol. 70,5288-5296

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Powell, M.D., Beard, W.A., Bebenek, K., Howard, K.J., Le Grice, S.F.J., Darden, T.A., KUI1kel, T.A., Wilson, S.H., and Levin, J.G. (1999) Residues in the alpha H and alpha I Helices of the mv-1 Reverse Transcriptase Thumb Subdomain Required for the Specificity of RNase H-catalyzed Removal of the Polypurine Tract Primer. J. BioI. Chem. 274,19885-19893.


Huang, M-B, Khan, M., Garcia-Barrio, M., Powell, M.D., and Bond, V.C. (2001) Apoptotic Effects in Primary Human Umbilical Vein Endothelial Cell Cultures Caused by Exposure to Virion-Associated and Cell Membrane-Associated HIV- gp120. I. Acquir. Immune Defic. Syndr. 27: 213-221.