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Neuroscience Institute
Morehouse School of Medicine
720 Westview Drive
Atlanta, GA. 30310
Byron D. Ford, Ph.D.  

Selected Publications

Clement C.M., Thomas, L.K, Mou, Y., Croslan D.R., Gibbons, G.H., Ford B.D. (2006) Neuregulin-1 Attenuates Neointimal Formation Following Vascular Injury and Inhibits the Proliferation of Vascular Smooth Muscle Cells, J. Vasc. Res. (in Press)

Xu Z., Croslan D.R., Harris A.E., Ford. G.D., Ford B.D. (2006) Extended therapeutic window for intravascular administration of neuregulin-1 following focal ischemic stroke. J. Cereb. Blood Flow Metab. 26(4):527-535 .

Ford G.D., Xu Z., Gates, A., Jiang J., Ford, B.D. (2006) Expression Analysis Systematic Explorer (EASE) Analysis Reveals Differential Gene Expression in Permanent and Transient Focal Stroke Rat Models. Brain Res. 1071(1): 226-236.

Bhat G.K., Sea T.L., Olatinwo M., Simorgankir D., Ford G.D., Ford B.D. , Mann D.R. (2006) Expression levels of apoptosis-related genes in the testis of leptin-deficient mice. J. Androl. 27(2):302-310.

Dorsey W.C., Tchounwou P.B., Ford B.D. (2006) Neuregulin 1-Beta Cytoprotective Role in AML 12 Mouse Hepatocytes Exposed to Pentachlorophenol. Int J Environ Res Public Health. 3(1):11-22.

Xu Z., Ford G.D., Croslan D., Jiang J., Gates A., Allen R., Ford B.D. , (2005) Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression. Neurobiol. Disease. 19(3): 461-470.

Xu. Z. and Ford B.D. (2005) Upregulation of erbB receptors in rat brain after middle cerebral arterial occlusion. Neurosci. Lett. 375(3):181-186.

Liu Y., Ford B.D. , Mann M.A., Fischbach G.D. (2005) Neuregulin-1 increases the proliferation of neuronal progenitors from embryonic neural stem cells Dev. Biol. 283(2): 437-445.

Dorsey W.C., Ford B.D. , Roane L., Haynie D.T., Tchounwou P.B. (2005) Induced mitogenic activity in AML-12 mouse hepatocytes exposed to low-dose ultra-wideband electromagnetic radiation. Int. J. Environ. Res. Public Health. 2(1): 24–30

Bhat G.K., Sea T.L., Olatinwo M., Simorgankir D., Ford G.D., Ford B.D. , Mann D.R. (2005) Expression levels of apoptosis-related genes in the testis of leptin-deficient mice. J. Androl. 27(3):

Xu Z., Jiang J., Ford. G.D., Ford B.D. (2004) Neuregulin-1 is neuroprotective and attenuates inflammatory responses induced by ischemic stroke. Biochem. and Biophys. Res. Comm. 322:440-446.

Ford B.D. , Han B., Fischbach G.D. (2003) Differentiation-dependent regulation of myogenesis in skeletal myoblasts by Neuregulin-1. Biochem. and Biophys. Res. Comm. 306:276-281

Ford B.D., Mann M.A., Liu Y., Krauss R., Phillips K., Gan L., Fischbach G.D. (2003) Neuregulin-1 suppresses muscarinic receptor expression and acetylcholine-activated muscarinic K + channels in cardiac myocytes. Biochem. and Biophys. Res. Comm. 308:23-28.

Rosen K.M., Ford B.D. , Querfurth H.W. (2003) Downregulation and increased turnover of β-Amyloid Precursor Protein in skeletal muscle cultures by Neuregulin-1. Exp. Neurol. 181(2):170-180.

Chen Y., McCarron R.M., Golech S., Bembry J., Ford B. , Lenz F.A., Azzam N., Spatz M. (2003) Signal transduction pathway involved in ET-1 and NO-mediated interactions in human brain capillary endothelial responses. Am. J. Physiol. Cell Physiol. 284(2):C243-249

Parker M.W., Chen Y., Hallenbeck J.M., Ford B.D. (2002) Neuregulin expression after focal stroke in the rat. Neurosci. Lett. 334(3): 169-172.

Liu Y., Ford B. , Mann M.A. and Fischbach G.D. (2001) Neuregulin increases a 7 nAChRs and enhances excitatory synaptic transmission in GABAergic interneurons of hippocampus. J. Neurosci. 21(15): 5660-5669.

Ford B.D. , Loeb J.A. and Fischbach G.D. (1999) Neuregulin stimulates DNA synthesis in cultured chick heart cells. Dev. Biol. 214:139-150.

Ford B.D. , Ivy M.T., Mtshali C.P. Townsel J.G. (1999) The involvement of protein kinase C in the regulation of choline cotransport in Limulus. Comp. Biochem. And Physiol. 123A:255-261

Floyd E.A., Young-Seigler A.C., Ford B.D. , Reasor J.D., Moore E.L., Townsel J.G., Rucker H.K. (1996) Chronic ethanol ingestion produces cholinergic hypofunction in rat brain. Alcohol. 14: 1-6

Ford B.D. , Dorsey W.C., Townsel, J.G. (1995) Differential expression and subcellular localization of protein kinase C isoforms in neuronal and cardiac tissues of Limulus polyphemus. Biochem. and Biophys. Res. Comm. 208(2): 463-469.

Ford B.D. , Dorsey W.C., Townsel, J.G. (1995) Neurotransmitter and neuropeptide modulation of high affinity choline uptake in Limulus brain. Comp. Biochem. and Physiol. 111A: 147-153.


Pending Manuscripts:

Croslan D.R., Clement C.M., Gates, A., Harris A.E., Ford B.D. (2007) Neuroprotective and Anti-apoptotic effects of Neuregulin-1 on B35 Neuronal Cells following Ischemia: a Role for the PI3K/Akt Pathway (Submitted)

Li Y., Xu Z., Ford G.D., Croslan D.R., Harris A.E., Cairobe T., Li Z., Ford B.D. (2007) Neuroprotection by Neuregulin-1 in a Rat Model of Permanent Focal Cerebral Ischemia: Synergistic Treatment with the Glutamate Antagonist MK-801 (Submitted)

Ford G.D., Ford B.D. , Gates A., MacLeish P.R. (2007) Analysis of Transcriptional Profiles and Functional Clustering of Global Cerebellar Gene Expression in PCD3J Mice. (Submitted).

Ford G.D., Gates, A., Moreno C.S., Xu Z., Ford, B.D. (2007) Computational identification of conserved transcription factor binding sites upstream of genes induced by focal ischemic stroke. (Manuscript in Preparation).

Ford G.D., Mann M.A., Fortson W., Gates A., Fischbach G.D., Ford B.D. (2007) Molecular Profiling of Neuregulin-1 Heterozygous Mice Reveals the Dysregulation of Genes Linked to Schizophrenia. (Manuscript in Preparation).