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Neuroscience Institute
Morehouse School of Medicine
720 Westview Drive
Atlanta, GA. 30310
Chiaki Fukuhara, Ph.D.   

Selected Publications

Fukuhara, C., Yamazaki, S., Liang, J. Pineal circadian clocks gate arylalkylamine N-acetyltransferase gene expression in the mouse pineal gland. J Neurochem 93 (2005) 156-162.

Fukuhara, C. Effect of dark exposure in the middle of the day on Period1, Period2, and arylalkylamine N-acetyltansferase mRNA levels in the rat suprachiasmatic nucleus and pineal gland. Mol Brain Res 130 (2004) 109-114.

Liang, J., Wessel, J.H., Iuvone, P.M., Tosini, G., Fukuhara, C. Diurnal rhythms of tryptophan hydroxylase1 and 2 mRNA expression in the rat retina. NeuroReport 15 (2004) 1497-500.

Paul, K.N., Gamble, K.L., Fukuhara, C., Novak, C., Tosini, G., Albers, E.H. Tetrodotoxin prevents the decrease of melatonin levels the pineal gland without influencing Per1 and Per2 mRNA levels in the suprachiasmatic nucleus (SCN). Euro J Neurosci 19 (2004) 2808-2814.

Fukuhara, C., Liu, C., Ivanova, T.N., Chan, G.C.K., Storm, D.R., Iuvone, P.M., Tosini, G., Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retina. J. Neurosci. 24 (2004) 1803-1811.

Fukuhara, C. and Tosini, G. Peripheral circadian oscillators and their rhythmic regulation. Frontiers in Bioscience 8 (2003) 642-651.

Fukuhara, C., Dirden, J.C., Tosini, G., Analysis of gene expression following norepinephrine stimulation in the rat pineal gland using DNA microarray technique. J. Pineal Research 35 (2003) 196-203.

Paul, K., Fukuhara, C., Tosini, G., and Albers, E. Transduction of light in the suprachiasmatic nucleus: Evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin. Neuroscince 119 (2003) 137-144.

Fukuhara, C., Dirden, J.C., and Tosini, G., Regulation of period1 expression in cultured rat pineal, NeuroSignals 11 (2002) 103-114.

Fukuhara, C., Dirden, J.C., and Tosini, G., Circadian expression of Period 1, Period 2, and Arylalkylamine N-acetyltransferase mRNA in the rat pineal gland under different light conditions. Neurosci. Lett. 286 (2000) 167-170.

Lecea, L., Kilduff, T.S., Peyron, C., Gao, X.-B., Foye, P.E., Danielson, P.E., Fukuhara, C., Battenberg, E.L.F., Gautvik, V.T., Bartlett, F.S., Frankel, W.N., van den pol, A.N., Bloom, F.E., Gautvik, K.M., and Sutcliffe, J.G., The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. USA, 95 (1998) 322-327.

Tei, H., Okamura, H., Shigeyoshi, Y., Fukuhara, C., Ozawa, R., Hirose, M.,and Sakaki, Y., Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature, 389 (1997) 512-516.

Fukuhara, C., Hamada, T., Shibata, S., Watanabe, S., Aoki, K., and Inouye, S.-I. T., Phase advances of circadian rhythms in somatostatin depleted rats: effects of cysteamine on rhythms of locomotor activity and electrical discharge of the suprachiasmatic nucleus. J. Comp. Physiol. A, 175 (1994) 677-685.

Fukuhara, C., Nishiwaki, T., Cagampang, F. R. A., and Inouye, S.-I. T., Emergence of VIP rhythmicity following somatostatin depletion in the rat suprachiasmatic nucleus. Brain Res., 645 (1994) 343-346.

Shinohara, K., Tominaga, K., Fukuhara, C., Otori, Y., and Inouye, S.-I. T., Processing of photic information within the intergeniculate leaflet of the lateral geniculate body: assessed by neuropeptide Y immunoreactivity in the suprachiasmatic nucleus of rats. Neuroscience, 56 (1993) 813-822.

Fukuhara, C., Shinohara, K., Tominaga, K., Otori, Y., and Inouye, S.-I. T., Endogenous circadian rhythmicity of somatostatin like-immunoreactivity in the rat suprachiasmatic nucleus. Brain Res., 606 (1993) 28-35.