Paul, K.N. , Fukuhara, C., Tosini, G., Albers, H.E. (2003) Transduction of light in the SCN: Evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin. Neuroscience 119: 137-144.

Gamble, K.L., Novak, C. M., Paul, K.N., Albers, H.E. (2003) The ability of NMDA to mimic the effects of light in the suprachiasmatic nucleus requires sodium-dependent action potentials during the day but not at night. Neuroreport 14: 641-644.

Paul, K.N ., Gamble, K.L., Fukuhara, C., Novak, C. M., Tosini, G., Albers, H.E. (2004) Tetrodotoxin blocks the effects of light on the pineal gland without influencing Per1 and Per2 mRNA levels in the suprachiasmatic nucleus (SCN). Eur. J. Neurosci., 19: 2808-2814.

 Paul, K.N. , Fukuhara, C., Karom, M.C., Tosini, G., Albers, H.E. (2005) AMPA/kainate receptor antagonist DNQX blocks the acute increase of Per1 and Per2 mRNA levels in most but not all areas of the SCN. Mol. Brain Res., 13: 129-136.

Gamble, K.L., Paul, K.N., Karom, M.C., Tosini, G., Albers, H.E. (2006) Paradoxical effects of NPY in the suprachiasmatic nucleus. Eur. J. Neurosci. In Press.

 Paul, K.N. , Dugovic, C., Turek, F.W., Laposky, A.D. (2006) Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function. Sleep. In Press.

Ehlen, J.C., Novak, C.M., Karom, M.C., Gamble, K.L., Paul, K.N., Albers, H.E. (2006) GABA A receptor activation suppresses Period 1 and Period 2 mRNA in the suprachiasmatic nucleus during the mid-subjective day. Eur. J. Neurosci. In Press.

Novak, C.M., Ehlen, J.C., Paul, K.N., Fukuhara, C., Albers, H.E. (2006) Light and GABA A receptor activation alter rhythmic Period mRNA levels in the SCN of diurnal grass rats: Independent and additive effects. Eur. J. Neurosci. Submitted.

 

Published Abstracts and Poster Presentations :

Paul, K.N. , Dirden, J., Casano, A.A., Mintz, E.M., Tosini, G., Albers, H.E. Microinjection of NMDA into the SCN region suppresses the Nocturnal Rise of Pineal Melatonin Levels in Hamsters. 29 th Annual Meeting Society for Neuroscience, Miami, FL, 1999.

Paul, K.N. , Shand S., Mintz, E.M., Albers H.E. Substance P in the Suprachiasmatic Nucleus: Role in Circadian Entrainment. 30 th Annual Meeting Society for Neuroscience, New Orleans, LA, 2000.

Novak, C.M., Bult, A., Paul, K.N., Smale, L., Tosini, G., and Albers H.E. Daily rhythm of pineal melatonin content in the diurnal murid rodent, Arvicanthis niloticus. Seventh Meeting Society for Research on Biological Rhythms, Amelia Island , Fl, 2000 .

Paul, K.N. , Fukuhara, C., Tosini, G., Albers, H.E. AP5 suppresses light-induced Per1 gene expression in Syrian hamsters. Gordon Research Conference for Chronobiology, Newport, RI, 2001.

Paul, K.N. , Fukuhara, C., Tosini, G., Albers, H.E. AP5 blocks Per1 gene expression but not pineal melatonin suppression in Syrian hamsters. 31 st Annual Meeting Society for Neuroscience , San Diego, CA, 2001.

Paul, K.N. Excitatory amino acid (EAA) receptors differentially regulate the acute effects of light in the suprachiasmatic nucleus (SCN). 18 th Annual South East Nerve Net Conference, Atlanta, GA, 2002.

Paul, K.N. , Fukuhara, C., Tosini, G., Albers, H.E. A non-NMDA receptor antagonist blocks Per1 gene expression but not pineal melatonin suppression in Syrian Hamsters. Eighth Meeting Society for Research on Biological Rhythms, Amelia Island, Fl, 2002.

Paul, K.N. , Gamble, K.L., Novak, C.M., Tosini, G., Albers, H.E. Tetrodotoxin inhibits light-induced Per1 gene expression in the suprachiasmatic nucleus. 32 nd Annual Meeting Society for Neuroscience, Orlando, FL, 2002.

Paul, K.N. , Carlin, K.M., Turek, F.W., Laposky, A.D. Mice display gender differences in total sleep time, distribution and recovery from sleep deprivation. 24 th Annual Minisymposium Center for Reproductive Science, Northwestern University, Evanston, IL, 2003.

Gamble, K.L., Paul, K.N., Karom, M.C., Smith, D.A., Albers, H.E. NPY reduces light-induced Per1 gene expression in the SCN during the late night. 33 rd Annual Meeting Society for Neuroscience, New Orleans, LA, 2003.

Paul, K.N. , Carlin, K.M., Turek, F.W., Laposky, A.D. Mice display sex differences in wake time, sleep time, and recovery from sleep deprivation. 18 th Annual Meeting Associated Professional Sleep Societies, Philadelphia, PA, 2004.

Paul, K.N. , Dugovic, C., Losee-Olson, S., Laposky, A.D., Turek, F.W. “Sleepless” mice display increased levels of daily locomotor activity. Ninth Meeting Society for Research on Biological Rhythms, Whistler, British Columbia, 2004.

Novak, C.M., Ehlen, J.C., Paul, K.N., Karom, M.C., Picel, A., Akpa, M., Albers, H.E. Light and GABA interact to alter Period mRNA levels in the SCN of diurnal grass rats. Ninth Meeting Society for Research on Biological Rhythms, Whistler, British Columbia, 2004.

Dugovic C., Chung, B.Y., Perrino, N.M., Laposky, A.D., Losee-Olson, S., Paul, K.N., Horton, T.H. Turek, F.W. A heritable mutation, “Sleepless”, promotes active sleep in neonatal mice and wake in adults. 34 th Annual Meeting Society for Neuroscience, San Diego, CA, 2004.

Paul, K.N ., Caralis, D., Kalembar, C., Turek, F.W., Laposky, A.D. Gonadal hormones are responsible for sex differences in sleep and wakefulness in mice. UNCF/Merck Annual Fellows Day, New Brunswick, NJ, 2004.

Paul, K.N ., Losee, M.W., Turek, F.W., Shelton, J. The relationship between sleep and activity in mice: A comparison across strains. 19 th Annual Meeting Associated Professional Sleep Societies, Denver, CO, 2005.

Paul, K.N ., Caralis, D., Kalembar, C., Turek, F.W., Laposky, A.D. Gonadectomy eliminates sex differences in recovery from sleep deprivation and acute stress in mice. 19 th Annual Meeting Associated Professional Sleep Societies, Denver, CO, 2005.

Paul, K.N. , Losee, M.W., Turek, F.W., Shelton, J. The relationship between sleep and activity in mice: A comparison across strains. Gordon Research Conference for Chronobiology, Newport, RI, 2005.

Gamble, K.L., Karom, M.C., Paul, K.N., Tosini, G., Albers, H.E. Activation of NPY Y5 receptors in the SCN suppresses pineal melatonin during the late night. 35 th Annual Meeting Society for Neuroscience, Washington, DC, 2005.

Paul, K.N. , Losee, M.W., Simkin, D., Turek, F.W., Shelton, J. Sleep-Wake Architecture Exhibits a Genetic Relationship to Daily Fluctuations of Locomotor Activity. 20 th Annual Meeting Associated Professional Sleep Societies, Salt Lake City, UT, 2006.